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What are the recommended first-line treatments for managing menopausal symptoms in primary care?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 14 August 2025

Offer hormone replacement therapy (HRT) to people with vasomotor symptoms associated with menopause 1.

For women with a uterus, combined HRT should be offered, and for those who have had a total hysterectomy, oestrogen-only HRT should be offered 1.

Consider menopause-specific cognitive behavioural therapy (CBT) as an option for vasomotor symptoms, either in addition to HRT or when HRT is contraindicated or not preferred 1.

Do not routinely offer SSRIs, SNRIs, or clonidine as first-line treatment for vasomotor symptoms alone 1.

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This content was generated by iatroX. Always verify information and use clinical judgment.