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What are the key clinical features to consider when diagnosing Systemic Lupus Erythematosus (SLE) in a primary care setting?
Answer
Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 14 August 2025
When considering systemic lupus erythematosus (SLE) in a primary care setting, it is crucial for primary care physicians to be aware of its diverse and sometimes unusual presentations [Pramanik, 2014]. Knowledge of these varied manifestations is essential to aid in diagnosis [Pramanik, 2014]. Furthermore, identifying risk factors and understanding pathways for clinical care are important considerations that can contribute to early recognition of SLE [Choi et al., 2016].
Key References
- CKS - Sarcoidosis
- CKS - Spondyloarthritis and psoriatic arthropathy
- NG95 - Lyme disease
- NG100 - Rheumatoid arthritis in adults: management
- CKS - Rheumatoid arthritis
- NG12 - Suspected cancer: recognition and referral
- (Pramanik, 2014): Diagnosis of systemic lupus erythematosus in an unusual presentation: what a primary care physician should know.
- (Choi et al., 2016): Preventing the development of SLE: identifying risk factors and proposing pathways for clinical care.
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