clinical q&a library

Explore a database of clinical questions answered by iatroX, referencing established clinical guidelines, SmPCs, and peer-reviewed literature.

What are the current guidelines for the management of glioblastoma multiforme in terms of surgical intervention and adjuvant therapies?

For newly diagnosed glioblastoma multiforme (grade 4 glioma), surgical resection should be considered to obtain a histological and molecular diagnosis and to...

22 Aug 2025View Answer

How should I approach the referral process for a patient suspected of having glioblastoma multiforme, and what information should I include?

When referring a patient suspected of having glioblastoma multiforme, offer a standard structural MRI (T2 weighted, FLAIR, DWI series, and T1 pre- and post-c...

22 Aug 2025View Answer

What imaging modalities are recommended for the diagnosis and assessment of glioblastoma multiforme in primary care?

Recommended imaging modalities for diagnosis and assessment of glioblastoma multiforme (GBM) in primary care:Offer standard stru...

22 Aug 2025View Answer

What are the key clinical features that suggest a diagnosis of glioblastoma multiforme in a patient presenting with neurological symptoms?

Key clinical features suggesting glioblastoma multiforme (GBM) in a patient presenting with neurological symptoms include:New on...

22 Aug 2025View Answer

What lifestyle modifications should I advise to patients diagnosed with primary open-angle glaucoma?

Lifestyle modifications for patients diagnosed with primary open-angle glaucoma (POAG) should focus on supporting adherence to treatment and regular ...

22 Aug 2025View Answer

When should I consider referring a patient with primary open-angle glaucoma to an ophthalmologist?

Consider referring a patient with primary open-angle glaucoma (POAG) to an ophthalmologist if any of the following are present:T...

22 Aug 2025View Answer

What are the current NICE guidelines for the pharmacological management of primary open-angle glaucoma?

The NICE guidelines recommend offering 360° selective laser trabeculoplasty (SLT) as initial treatment for people with newly diagnosed chronic open-angle gla...

22 Aug 2025View Answer

How should I monitor intraocular pressure in patients diagnosed with primary open-angle glaucoma?

Intraocular pressure (IOP) monitoring in patients diagnosed with primary open-angle glaucoma (POAG) should be performed using Goldmann applanation to...

22 Aug 2025View Answer

What are the recommended initial diagnostic tests for a patient suspected of having primary open-angle glaucoma?

To diagnose primary open-angle glaucoma, offer all of the following tests: visual field assessment using standard automated perimetry (full threshold or supr...

22 Aug 2025View Answer

What patient education should I provide regarding the risk factors and prevention of acute angle-closure glaucoma?

Patient education regarding risk factors and prevention strategies for acute angle-closure glaucoma should include the following key points:...

22 Aug 2025View Answer

Which diagnostic tests are essential for confirming acute angle-closure glaucoma in a primary care setting?

In a primary care setting, the essential diagnostic tests to confirm acute angle-closure glaucoma include:Intraocular pressure (IOP) meas...

22 Aug 2025View Answer

What are the criteria for urgent referral of a patient with suspected acute angle-closure glaucoma to an ophthalmologist?

Criteria for urgent referral of a patient with suspected acute angle-closure glaucoma to an ophthalmologist include:Presence of ...

22 Aug 2025View Answer

How should I initiate treatment for a patient with acute angle-closure glaucoma before referral to secondary care?

Initiate treatment for acute angle-closure glaucoma urgently before referral to secondary care by:Administering immediate medica...

22 Aug 2025View Answer

What are the key clinical features that suggest a diagnosis of acute angle-closure glaucoma in a patient presenting with eye pain?

Key clinical features suggesting acute angle-closure glaucoma in a patient presenting with eye pain include:Sudden onset...

22 Aug 2025View Answer

What is the role of antimicrobial therapy in the management of periodontitis in primary care?

Antimicrobial therapy in the management of periodontitis in primary care has a limited and adjunctive role rather than being a primary treatment moda...

22 Aug 2025View Answer

Which systemic conditions should I consider when evaluating a patient with severe periodontitis?

When evaluating a patient presenting with severe periodontitis, several systemic conditions should be considered due to their known associations with periodo...

22 Aug 2025View Answer

What are the referral criteria for patients with periodontitis to a specialist periodontist?

Referral criteria for patients with periodontitis to a specialist periodontist are not explicitly detailed in the provided UK guidelines. Ho...

22 Aug 2025View Answer

What are the key clinical features that differentiate gingivitis from periodontitis in adult patients?

The key clinical features that differentiate gingivitis from periodontitis in adult patients primarily relate to the extent of tissue involvement and...

22 Aug 2025View Answer

What are the first-line treatment options for giardiasis in children?

First-line treatment options for giardiasis in children primarily include 5-nitroimidazole compounds such as metronidazole, which is widely ...

22 Aug 2025View Answer

What are the recommended diagnostic tests for confirming a Giardia lamblia infection in adults?

The recommended diagnostic tests for confirming Giardia lamblia infection in adults primarily involve stool analysis. The first-line approac...

22 Aug 2025View Answer
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