What are the key indications for referring a patient for an MRI scan in primary care?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025Updated: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Key indications for referring a patient for an MRI scan in primary care include:

  • Clinical suspicion of spinal metastases without signs of metastatic spinal cord compression (MSCC), where MRI should be performed within 1 week to guide treatment options .
  • Suspected primary brain tumours or brain metastases, where standard structural MRI is the initial diagnostic test unless contraindicated .
  • New or changing neurological symptoms or signs suggestive of glioma or other brain tumours, warranting MRI for diagnosis or monitoring .
  • Suspected multiple sclerosis (MS) based on neurological symptoms such as visual loss, double vision, sensory disturbances, or progressive balance difficulties, after excluding alternative diagnoses and confirming a neurological episode .
  • Any urgent neurological symptoms that require immediate diagnosis to start treatment, potentially justifying overnight MRI .

In addition, MRI is preferred over plain X-rays for spinal pathology and should be considered when CT is contraindicated or insufficient . Referral for MRI should be made when clinical features suggest serious underlying pathology requiring detailed imaging for diagnosis and management planning.

Educational content only. Always verify information and use clinical judgement.