clinical q&a library
Explore a database of clinical questions answered by iatroX, referencing established clinical guidelines, SmPCs, and peer-reviewed literature.
What initial assessments should I perform in a patient presenting with signs of major haemorrhage?
Initial assessments for a patient presenting with signs of major haemorrhage include:Clinical assessment of haemodynamic...
How can I interpret MRI results to guide management decisions in my patients?
Interpreting magnetic resonance imaging (MRI) results to guide management decisions requires understanding the clinical context, the specific MRI sequences u...
How do I determine whether an MRI is necessary for a patient with suspected musculoskeletal disorders?
To determine whether magnetic resonance imaging (MRI) is necessary for a patient with suspected musculoskeletal disorders, consider the following key points:...
What are the key indications for referring a patient for an MRI scan in primary care?
Key indications for referring a patient for an MRI scan in primary care include:Clinical suspicion of spinal metastases without ...
What follow-up tests are recommended for a patient with macrocytosis after initial treatment for vitamin B12 deficiency?
Follow-up tests for a patient with macrocytosis after initial treatment for vitamin B12 deficiency should not include repeating the initial ...
How should I manage a patient with macrocytosis who is also presenting with neurological symptoms?
Management of a patient presenting with macrocytosis and neurological symptoms should prioritise prompt assessment and treatment of possible vitamin ...
What are the indications for referring a patient with macrocytosis to a haematologist?
Indications for referring a patient with macrocytosis to a haematologist include:Presence of unexplained macrocytosis after init...
How do I differentiate between vitamin B12 deficiency and folate deficiency in a patient with macrocytosis?
To differentiate between vitamin B12 deficiency and folate deficiency in a patient presenting with macrocytosis, initial clinical and laboratory assessment i...
What initial investigations should I perform for a patient with macrocytosis and no obvious symptoms?
For a patient presenting with macrocytosis without obvious symptoms, the initial investigation should include testing for vitamin B12 deficiency using either...
What are the implications of a Lynch Syndrome diagnosis for the patient's family members in terms of screening and prevention?
A diagnosis of Lynch syndrome in a patient has significant implications for their family members, primarily concerning genetic risk, screening, and preventio...
When should I refer a patient for genetic counseling regarding Lynch Syndrome?
Refer a patient for genetic counseling regarding Lynch syndrome if they have a personal or family history suggestive of mismatch repair (MMR) gene pa...
What are the recommended surveillance protocols for patients diagnosed with Lynch Syndrome?
Recommended surveillance protocols for patients diagnosed with Lynch syndrome include:Consideration of daily aspirin for more th...
How should I approach genetic testing for Lynch Syndrome in patients with a family history of colorectal or endometrial cancer?
Approach genetic testing for Lynch syndrome in patients with a family history of colorectal or endometrial cancer by first assessing their risk of carrying p...
What are the key clinical features that suggest a diagnosis of Lynch Syndrome in a patient?
Key clinical features suggesting a diagnosis of Lynch syndrome include:Early-onset colorectal cancer, typically diagnosed before...
How can I effectively monitor disease activity and treatment response in patients with SLE in a general practice setting?
Effective monitoring of disease activity and treatment response in patients with systemic lupus erythematosus (SLE) in general practice involves regu...
When should I consider referring a patient with SLE to a specialist, and what information should I include in the referral?
When to refer a patient with systemic lupus erythematosus (SLE) to a specialist:Refer patients with suspected or confirmed SLE t...
What are the recommended management strategies for a patient with mild SLE symptoms in primary care?
In primary care, management of a patient with mild systemic lupus erythematosus (SLE) symptoms should focus on symptom control, prevention of disease progres...
What are the key clinical features to consider when diagnosing systemic lupus erythematosus (SLE) in a primary care setting?
When diagnosing systemic lupus erythematosus (SLE) in a primary care setting, key clinical features to consider include a combination of constitutional, muco...
When should I consider referring a patient for a lumbar puncture versus managing them in primary care?
Consider referring a patient for lumbar puncture when there is suspicion of serious central nervous system infection such as bacterial meningitis or ...