clinical q&a library

Explore a database of clinical questions answered by iatroX, referencing established clinical guidelines, SmPCs, and peer-reviewed literature.

What are the current transfusion protocols for managing massive blood loss in adults?

For adults with massive blood loss, the current transfusion protocol involves using a fixed‑ratio protocol of 1 unit of plasma to 1 unit of red blood cells, ...

22 Aug 2025View Answer

What initial assessments should I perform in a patient presenting with signs of major haemorrhage?

Initial assessments for a patient presenting with signs of major haemorrhage include:Clinical assessment of haemodynamic...

22 Aug 2025View Answer

How can I interpret MRI results to guide management decisions in my patients?

Interpreting magnetic resonance imaging (MRI) results to guide management decisions requires understanding the clinical context, the specific MRI sequences u...

22 Aug 2025View Answer

How do I determine whether an MRI is necessary for a patient with suspected musculoskeletal disorders?

To determine whether magnetic resonance imaging (MRI) is necessary for a patient with suspected musculoskeletal disorders, consider the following key points:...

22 Aug 2025View Answer

What are the key indications for referring a patient for an MRI scan in primary care?

Key indications for referring a patient for an MRI scan in primary care include:Clinical suspicion of spinal metastases without ...

22 Aug 2025View Answer

What follow-up tests are recommended for a patient with macrocytosis after initial treatment for vitamin B12 deficiency?

Follow-up tests for a patient with macrocytosis after initial treatment for vitamin B12 deficiency should not include repeating the initial ...

22 Aug 2025View Answer

How should I manage a patient with macrocytosis who is also presenting with neurological symptoms?

Management of a patient presenting with macrocytosis and neurological symptoms should prioritise prompt assessment and treatment of possible vitamin ...

22 Aug 2025View Answer

What are the indications for referring a patient with macrocytosis to a haematologist?

Indications for referring a patient with macrocytosis to a haematologist include:Presence of unexplained macrocytosis after init...

22 Aug 2025View Answer

How do I differentiate between vitamin B12 deficiency and folate deficiency in a patient with macrocytosis?

To differentiate between vitamin B12 deficiency and folate deficiency in a patient presenting with macrocytosis, initial clinical and laboratory assessment i...

22 Aug 2025View Answer

What initial investigations should I perform for a patient with macrocytosis and no obvious symptoms?

For a patient presenting with macrocytosis without obvious symptoms, the initial investigation should include testing for vitamin B12 deficiency using either...

22 Aug 2025View Answer

What are the implications of a Lynch Syndrome diagnosis for the patient's family members in terms of screening and prevention?

A diagnosis of Lynch syndrome in a patient has significant implications for their family members, primarily concerning genetic risk, screening, and preventio...

22 Aug 2025View Answer

When should I refer a patient for genetic counseling regarding Lynch Syndrome?

Refer a patient for genetic counseling regarding Lynch syndrome if they have a personal or family history suggestive of mismatch repair (MMR) gene pa...

22 Aug 2025View Answer

What are the recommended surveillance protocols for patients diagnosed with Lynch Syndrome?

Recommended surveillance protocols for patients diagnosed with Lynch syndrome include:Consideration of daily aspirin for more th...

22 Aug 2025View Answer

How should I approach genetic testing for Lynch Syndrome in patients with a family history of colorectal or endometrial cancer?

Approach genetic testing for Lynch syndrome in patients with a family history of colorectal or endometrial cancer by first assessing their risk of carrying p...

22 Aug 2025View Answer

What are the key clinical features that suggest a diagnosis of Lynch Syndrome in a patient?

Key clinical features suggesting a diagnosis of Lynch syndrome include:Early-onset colorectal cancer, typically diagnosed before...

22 Aug 2025View Answer

How can I effectively monitor disease activity and treatment response in patients with SLE in a general practice setting?

Effective monitoring of disease activity and treatment response in patients with systemic lupus erythematosus (SLE) in general practice involves regu...

22 Aug 2025View Answer

When should I consider referring a patient with SLE to a specialist, and what information should I include in the referral?

When to refer a patient with systemic lupus erythematosus (SLE) to a specialist:Refer patients with suspected or confirmed SLE t...

22 Aug 2025View Answer

What are the recommended management strategies for a patient with mild SLE symptoms in primary care?

In primary care, management of a patient with mild systemic lupus erythematosus (SLE) symptoms should focus on symptom control, prevention of disease progres...

22 Aug 2025View Answer

What are the key clinical features to consider when diagnosing systemic lupus erythematosus (SLE) in a primary care setting?

When diagnosing systemic lupus erythematosus (SLE) in a primary care setting, key clinical features to consider include a combination of constitutional, muco...

22 Aug 2025View Answer

When should I consider referring a patient for a lumbar puncture versus managing them in primary care?

Consider referring a patient for lumbar puncture when there is suspicion of serious central nervous system infection such as bacterial meningitis or ...

22 Aug 2025View Answer
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