Opioid overdose — DIPIMC MCQ
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Correct answer: D — Support ventilation and give titrated naloxone to restore adequate breathing.
Opioid toxicity with respiratory depression is managed by supporting ventilation and titrating naloxone to restore adequate breathing rather than full arousal, recognising its short duration of action. Flumazenil reverses benzodiazepines, not opioids. A large single bolus can precipitate acute withdrawal and agitation, and the patient may re-sedate as the naloxone wears off.
Reference: JRCALC Clinical Guidelines