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Gallbladder polyp — ESEGH MCQ

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HardGI CancerGallbladder polypESEGH

A patient with primary sclerosing cholangitis has ultrasound evidence of a new 9 mm sessile gallbladder polyp. What is the best response?

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Correct answer: BUrgent specialist hepatobiliary surgical assessment

The best answer is “Urgent specialist hepatobiliary surgical assessment”. PSC changes the malignancy threshold: even a sub-centimetre gallbladder lesion needs prompt specialist assessment. “Return to routine care given the polyp is below 10 mm” is less appropriate because PSC substantially increases gallbladder neoplasia risk “Repeat ultrasound in 5 years” is less appropriate because this interval is unsafe in a high-risk PSC context “ERCP with transpapillary gallbladder-polyp biopsy” is less appropriate because ERCP is not a reliable sampling method for a mural gallbladder lesion “Treat with ursodeoxycholic acid and assume resolution” is less appropriate because medical therapy does not eliminate a suspicious polyp

Reference: BSG/UK-PSC guideline: https://pmc.ncbi.nlm.nih.gov/articles/PMC6691863/