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Diabetic ketoacidosis — RACP Paediatrics MCQ

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HardEndocrinology and growthDiabetic ketoacidosisRACP Paediatrics

A 9-year-old presents with polyuria, weight loss, vomiting and abdominal pain. He is dehydrated with Kussmaul breathing; glucose is 28 mmol/L, ketones are high, pH is 7.16 and potassium is 4.8 mmol/L. What is the most appropriate management?

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Correct answer: ACareful intravenous fluids and insulin infusion with electrolyte monitoring

This is diabetic ketoacidosis, requiring protocolised IV fluids, insulin infusion and close electrolyte/neurological monitoring. Routine bicarbonate is not indicated and may increase risk unless there is exceptional severe compromise. The pearl is that cerebral injury risk is managed by careful fluids, monitoring and avoiding abrupt osmotic shifts.

Reference: RCH Clinical Practice Guidelines: Diabetic ketoacidosis; Therapeutic Guidelines (eTG); AMH Children's Dosing Companion