A 12-day-old infant with atypical genitalia presents with vomiting, poor feeding and weight loss. Sodium is 124 mmol/L, potassium is 6.8 mmol/L and

Question

A 12-day-old infant with atypical genitalia presents with vomiting, poor feeding and weight loss. Sodium is 124 mmol/L, potassium is 6.8 mmol/L and glucose is 2.1 mmol/L. What is the most appropriate management?

Accepted Answer

Hydrocortisone with saline, glucose and urgent endocrine consultation

Answer

Delayed treatment until karyotype confirms sex chromosome pattern

Answer

Fluid restriction for suspected syndrome of inappropriate ADH

Answer

Oral fludrocortisone alone and outpatient review

Answer

Empirical thyroxine for congenital hypothyroidism

Congenital adrenal hyperplasia — RACP Paediatrics MCQ

A 12-day-old infant with atypical genitalia presents with vomiting, poor feeding and weight loss. Sodium is 124 mmol/L, potassium is 6.8 mmol/L and glucose is 2.1 mmol/L. What is the most appropriate management?