A 43-year-old woman has episodic headache, sweating and palpitations with paroxysmal hypertension. Her mother had medullary thyroid carcinoma. ECG

Question

A 43-year-old woman has episodic headache, sweating and palpitations with paroxysmal hypertension. Her mother had medullary thyroid carcinoma. ECG between episodes is normal and potassium is 4.1 mmol/L. What is the most appropriate investigation?

Accepted Answer

Plasma free metanephrines or 24-hour urinary fractionated metanephrines

Answer

Random serum adrenaline during clinic review

Answer

Oral glucose tolerance test

Answer

Aldosterone-renin ratio as the sole test

Answer

Immediate adrenal biopsy

Phaeochromocytoma — RACP Adult Medicine MCQ

A 43-year-old woman has episodic headache, sweating and palpitations with paroxysmal hypertension. Her mother had medullary thyroid carcinoma. ECG between episodes is normal and potassium is 4.1 mmol/L. What is the most appropriate investigation?