skip to main content

Paracetamol overdose — RACP Adult Medicine MCQ

Instant feedback + full explanation. One question, done properly.

ModerateClinical pharmacology and toxicologyParacetamol overdoseRACP Adult Medicine

A 24-year-old woman presents 6 hours after taking 18 g of paracetamol. She feels nauseated but is alert. ALT is normal and the ingestion time is reliable. What is the most appropriate investigation?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — Timed plasma paracetamol concentration plotted on the treatment nomogram

A timed paracetamol concentration is used to decide acetylcysteine treatment after a single acute ingestion, although treatment should not be delayed if results are late. Early ALT can be normal despite toxic ingestion. Bilirubin, urine drug screen and chest radiography do not determine antidote need.

Reference: Australian Poisons Information guidance; AMH