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Gallstone pancreatitis with cholangitis — RACP Adult Medicine MCQ

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HardGastroenterology and hepatologyGallstone pancreatitis with cholangitisRACP Adult Medicine

A 45-year-old woman presents with epigastric pain radiating to the back. Lipase is 1600 U/L, bilirubin 94 micromol/L, temperature 38.7°C and ultrasound shows gallstones with a dilated common bile duct. She is hypotensive despite initial fluids. What is the most appropriate management?

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Correct answer: AUrgent ERCP with biliary decompression plus antibiotics and resuscitation

Gallstone pancreatitis complicated by cholangitis and obstruction requires urgent biliary drainage with ERCP, antibiotics and supportive care. Oral feeding alone is unsafe in sepsis and obstruction. Delayed cholecystectomy, corticosteroids and colonoscopy do not address the obstructed infected biliary system.

Reference: GESA pancreatitis guidance; Therapeutic Guidelines (eTG) Antibiotic