A 12-year-old girl has polyuria, weight loss and vomiting. Glucose is 28 mmol/L, ketones 5.6 mmol/L, pH 7.18 and bicarbonate 10 mmol/L; she is

Question

A 12-year-old girl has polyuria, weight loss and vomiting. Glucose is 28 mmol/L, ketones 5.6 mmol/L, pH 7.18 and bicarbonate 10 mmol/L; she is dehydrated but alert. What is the most likely cause?

Accepted Answer

Insulin deficiency causing ketosis and metabolic acidosis

Answer

Renal bicarbonate loss from tubular acidosis

Answer

Excess antidiuretic hormone causing water retention

Answer

Lactic acidosis from congenital heart disease

Answer

Salicylate poisoning with respiratory alkalosis

Diabetic ketoacidosis — MRCPCH FOP MCQ

A 12-year-old girl has polyuria, weight loss and vomiting. Glucose is 28 mmol/L, ketones 5.6 mmol/L, pH 7.18 and bicarbonate 10 mmol/L; she is dehydrated but alert. What is the most likely cause?