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Follow-up after peri-operative anaphylaxis — FRCA Final MCQ

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ModerateEthics, Human Factors and Patient SafetyFollow-up after peri-operative anaphylaxisFRCA Final

A patient has severe peri-operative anaphylaxis after teicoplanin but recovers. The operation is abandoned. In recovery the team is busy and the anaesthetic record contains incomplete drug timings. What is the most appropriate management?

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Correct answer: D — Take timed mast-cell tryptase samples and refer for allergy investigation

After suspected peri-operative anaphylaxis, timed mast-cell tryptase samples and specialist allergy referral are essential to identify the culprit and plan future anaesthesia. Blanket allergy labels can deny patients useful drugs and still miss the true trigger. Written information should be given to the patient and GP. Rechallenge without investigation is unsafe.

Reference: Resuscitation Council UK peri-operative anaphylaxis algorithm 2024; Association of Anaesthetists anaphylaxis guidance