Massive pulmonary embolism with RV failure — FRCA Final MCQ
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Correct answer: A — Give systemic thrombolysis after senior review
Massive PE with shock and RV failure is an indication for reperfusion therapy when bleeding risk is acceptable. Anticoagulation alone is too slow in haemodynamic collapse. Excessive PEEP and large fluid loading may worsen RV afterload and septal shift. Treatment should be coordinated with senior ICU, cardiology and haematology input.
Reference: ESC pulmonary embolism guideline; Faculty of Intensive Care Medicine standards