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Hereditary breast and ovarian cancer risk assessment — USMLE Step 3 MCQ

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HardAmbulatory Medicine / Primary CareHereditary breast and ovarian cancer risk assessmentUSMLE Step 3

A 38-year-old woman comes for preventive care. Her mother had ovarian cancer at 46 and her maternal aunt had breast cancer at 39. She has no breast symptoms and has not had genetic testing. She asks what screening or risk assessment is appropriate now. Which of the following is the most appropriate screening recommendation?

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Correct answer: ERefer for genetic counseling and BRCA-related risk assessment

A family history suggestive of hereditary breast and ovarian cancer warrants risk assessment and referral for genetic counseling and possible genetic testing rather than nonspecific ovarian screening with CA-125 or ultrasound.

Reference: USPSTF BRCA-related cancer risk assessment recommendation