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Uncomplicated gastroesophageal reflux disease — USMLE Step 3 MCQ

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ModerateAmbulatory Medicine / Primary CareUncomplicated gastroesophageal reflux diseaseUSMLE Step 3

A 44-year-old man has recurrent burning chest discomfort after meals and chronic cough. He has no dysphagia, bleeding, anemia, or weight loss. Examination is normal. He has not tried prescription therapy. Which of the following is the most likely diagnosis?

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Correct answer: B — Gastroesophageal reflux disease

Postprandial heartburn with chronic cough and no alarm features is most consistent with GERD. Initial management can include lifestyle measures and empiric acid suppression.

Reference: ACG GERD guideline