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Alcohol use disorder relapse prevention — USMLE Step 3 MCQ

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ModerateAmbulatory Medicine / Primary CareAlcohol use disorder relapse preventionUSMLE Step 3

A 48-year-old man with alcohol use disorder returns 2 weeks after detoxification. He has not used alcohol since discharge, has normal liver enzymes, and takes no opioids. He wants medication to reduce relapse risk and craving. Which of the following would you recommend at the follow-up visit?

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Correct answer: E — Start naltrexone with counseling and monitoring

Naltrexone reduces heavy drinking and craving in alcohol use disorder and is appropriate when the patient is not using opioids and has acceptable liver function. It should be combined with psychosocial support.

Reference: APA alcohol use disorder pharmacotherapy guidance