skip to main content

Acute cystitis in pregnancy — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

HardOB/GYNAcute cystitis in pregnancyUSMLE Step 3

A 26-year-old woman at 10 weeks' gestation has dysuria and urinary frequency. Urinalysis shows pyuria and nitrites. She is afebrile, has no flank pain, and has no drug allergies. Prior urine culture grew E coli susceptible to nitrofurantoin. Which of the following is the most appropriate at this time?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Treat with nitrofurantoin and send urine culture

Symptomatic cystitis in pregnancy should be treated promptly with a pregnancy-compatible antibiotic guided by local resistance and culture. Nitrofurantoin is commonly used outside contexts where it is contraindicated.

Reference: ACOG urinary tract infections in pregnancy guidance