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HIV prevention with PrEP — USMLE Step 3 MCQ

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ModerateAmbulatory Medicine / Primary CareHIV prevention with PrEPUSMLE Step 3

A 29-year-old man has sex with men and comes for preventive care. He had rectal gonorrhea 4 months ago, uses condoms inconsistently, and has a negative fourth-generation HIV test today. Creatinine and hepatitis B serologies are pending. He asks how to reduce his risk of HIV acquisition. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Discuss and offer HIV preexposure prophylaxis

Sexually active adults at ongoing risk should be informed about and offered PrEP after confirming HIV-negative status and assessing renal function and hepatitis B status for oral tenofovir-containing regimens.

Reference: CDC clinical guidance