A 59-year-old man has recurrent acute wrist and knee arthritis. Synovial fluid shows rhomboid weakly positively birefringent crystals. Hand

Question

A 59-year-old man has recurrent acute wrist and knee arthritis. Synovial fluid shows rhomboid weakly positively birefringent crystals. Hand radiographs show hook-like osteophytes at the second and third MCP joints. Ferritin and transferrin saturation are elevated. What is the most likely cause?

Accepted Answer

Hereditary hemochromatosis

Answer

Vitamin C deficiency

Answer

Primary hyperparathyroidism from parathyroid adenoma

Answer

Familial Mediterranean fever

Answer

Chronic lead poisoning

CPPD due to hemochromatosis — RCPSC IM MCQ

A 59-year-old man has recurrent acute wrist and knee arthritis. Synovial fluid shows rhomboid weakly positively birefringent crystals. Hand radiographs show hook-like osteophytes at the second and third MCP joints. Ferritin and transferrin saturation are elevated. What is the most likely cause?