Wilson disease — RCPSC IM MCQ
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Correct answer: D — Arrange emergency liver-transplant assessment while providing intensive supportive care
The best answer is “Arrange emergency liver-transplant assessment while providing intensive supportive care”. Acute or rapidly decompensating Wilson-related liver failure can be fatal without urgent transplantation. Chelation is important in stable disease but should not delay transplant assessment in fulminant deterioration. A prognostic index, trajectory and extrahepatic complications inform urgency, but referral should occur before irreversible multiorgan failure develops.
Reference: Canadian Association for the Study of the Liver: https://hepatology.ca/