Type 4 renal tubular acidosis — RCPSC IM MCQ
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Correct answer: D — Type 4 renal tubular acidosis
The best answer is “Type 4 renal tubular acidosis”. Diabetic kidney disease and drugs that reduce aldosterone signaling or distal potassium secretion produce hyperkalemic normal-anion-gap acidosis typical of type 4 RTA. Distal and proximal RTA are usually hypokalemic, while lactate and ethylene glycol produce high-anion-gap acidosis.
Reference: Current review of type 4 renal tubular acidosis in diabetes. https://pmc.ncbi.nlm.nih.gov/articles/PMC12289468/