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Candidemia from central venous catheter — RCPSC IM MCQ

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HardInfectious DiseasesCandidemia from central venous catheterRCPSC IM

An ICU patient has Candida glabrata in peripheral and central blood cultures and a central venous catheter. He is hemodynamically stable. What is the best initial management?

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Correct answer: AStart an echinocandin and remove the catheter when feasible

The best answer is “Start an echinocandin and remove the catheter when feasible”. Candidemia is clinically significant. C. glabrata often has azole resistance, making an echinocandin appropriate while susceptibility is defined; serial cultures document clearance and likely intravascular source control includes catheter removal. Topical or unvalidated low-dose treatment is inadequate.

Reference: AMMI Canada guideline for invasive candidiasis: https://pmc.ncbi.nlm.nih.gov/articles/PMC2806658/