Candidemia from central venous catheter — RCPSC IM MCQ
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Correct answer: A — Start an echinocandin and remove the catheter when feasible
The best answer is “Start an echinocandin and remove the catheter when feasible”. Candidemia is clinically significant. C. glabrata often has azole resistance, making an echinocandin appropriate while susceptibility is defined; serial cultures document clearance and likely intravascular source control includes catheter removal. Topical or unvalidated low-dose treatment is inadequate.
Reference: AMMI Canada guideline for invasive candidiasis: https://pmc.ncbi.nlm.nih.gov/articles/PMC2806658/