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Primary hyperparathyroidism — RCPSC IM MCQ

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ModerateEndocrinologyPrimary hyperparathyroidismRCPSC IM

A 64-year-old woman has recurrent renal stones and constipation. Corrected calcium is 2.86 mmol/L, phosphate is 0.72 mmol/L, PTH is elevated and 25-hydroxyvitamin D is sufficient. Creatinine is normal. There is no malignancy history. What is the most likely diagnosis?

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Correct answer: CPrimary hyperparathyroidism

Hypercalcemia with inappropriately high PTH, low phosphate and renal stones supports primary hyperparathyroidism.

Reference: Canadian endocrinology calcium disorder guidance