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Lithium toxicity — RACP Written MCQ

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ModerateClinical PharmacologyLithium toxicityRACP Written

A 59-year-old man with bipolar disorder presents with tremor, ataxia, vomiting and confusion after starting an ACE inhibitor for hypertension. Creatinine has risen and lithium toxicity is suspected. What is the most appropriate investigation?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Serum lithium concentration with renal function and electrolytes

Suspected lithium toxicity requires serum lithium measurement interpreted with renal function, electrolytes, timing of last dose and clinical severity.

Reference: AMH; Therapeutic Guidelines: Toxicology and drug-interaction principles