A 52-year-old woman develops fever, loin pain and hypotension 20 minutes after starting a red cell transfusion. Urine becomes dark and the

Question

A 52-year-old woman develops fever, loin pain and hypotension 20 minutes after starting a red cell transfusion. Urine becomes dark and the transfusion is stopped. Clerical mismatch is suspected. What is the most appropriate investigation?

Accepted Answer

Direct antiglobulin test with repeat compatibility testing

Answer

Serum vitamin B12

Answer

JAK2 mutation testing

Answer

Haemoglobin electrophoresis

Answer

Factor VIII level

Acute haemolytic transfusion reaction — RACP Written MCQ

A 52-year-old woman develops fever, loin pain and hypotension 20 minutes after starting a red cell transfusion. Urine becomes dark and the transfusion is stopped. Clerical mismatch is suspected. What is the most appropriate investigation?