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Antiphospholipid syndrome — RACP Written MCQ

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ModerateHaematologyAntiphospholipid syndromeRACP Written

A 34-year-old woman has three first-trimester miscarriages and a previous unprovoked pulmonary embolism. Lupus anticoagulant is positive on two occasions 14 weeks apart. Platelet count is mildly low. What is the most likely diagnosis?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: BAntiphospholipid syndrome

Recurrent pregnancy morbidity, prior thrombosis and persistent lupus anticoagulant positivity meet clinical and laboratory features of antiphospholipid syndrome.

Reference: Australian blood and haematology guideline principles; Therapeutic Guidelines