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Heparin-induced thrombocytopenia — RACP Written MCQ

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ModerateHaematologyHeparin-induced thrombocytopeniaRACP Written

A 61-year-old man is on day 8 after hip replacement and has been receiving unfractionated heparin. Platelets fall from 240 to 72 x 10^9/L and he develops a new femoral vein thrombosis. What is the most likely cause?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: AHeparin-induced thrombocytopenia

Timing 5 to 10 days after heparin exposure, platelet fall over 50% and new thrombosis strongly suggest immune-mediated heparin-induced thrombocytopenia.

Reference: Australian blood and haematology guideline principles; Therapeutic Guidelines