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Beta thalassaemia trait — RACP Written MCQ

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ModerateHaematologyBeta thalassaemia traitRACP Written

A 22-year-old woman from Thailand has microcytosis on screening. Hb is 112 g/L, MCV 62 fL, ferritin is normal and red cell count is high-normal. Hb electrophoresis shows raised HbA2. What is the most likely diagnosis?

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Correct answer: A — Beta thalassaemia trait

Marked microcytosis with normal ferritin, relatively preserved red cell count and raised HbA2 indicates beta thalassaemia trait.

Reference: Australian blood and haematology guideline principles; Therapeutic Guidelines