A 38-year-old woman has confusion, petechiae and renal impairment after a diarrhoeal illness. Platelets are 12 x 10^9/L, Hb is 82 g/L, schistocytes

Question

A 38-year-old woman has confusion, petechiae and renal impairment after a diarrhoeal illness. Platelets are 12 x 10^9/L, Hb is 82 g/L, schistocytes are present and coagulation studies are normal. Plasma exchange is being arranged. What is the most appropriate investigation?

Accepted Answer

ADAMTS13 activity and inhibitor testing

Answer

Serum ferritin alone

Answer

Serum tryptase

Answer

HLA-B27 testing

Answer

Direct antiglobulin test as sole test

Thrombotic thrombocytopenic purpura — RACP Written MCQ

A 38-year-old woman has confusion, petechiae and renal impairment after a diarrhoeal illness. Platelets are 12 x 10^9/L, Hb is 82 g/L, schistocytes are present and coagulation studies are normal. Plasma exchange is being arranged. What is the most appropriate investigation?