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Sjogren syndrome — RACP Written MCQ

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HardRheumatologySjogren syndromeRACP Written

A 38-year-old woman has dry eyes, dry mouth and recurrent parotid swelling. ANA is positive, anti-Ro antibody is positive and Schirmer test is abnormal. She now has purpura and low complement C4. What is the most important next step?

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Correct answer: E — Assess for lymphoma and systemic Sjogren complications

Sjogren syndrome with purpura and low complement raises concern for systemic disease and lymphoma risk, requiring specialist assessment.

Reference: Therapeutic Guidelines: Rheumatology; Australian rheumatology practice principles