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Scleroderma renal crisis — RACP Written MCQ

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HardRheumatologyScleroderma renal crisisRACP Written

A 49-year-old woman with diffuse systemic sclerosis develops severe headache and blood pressure 218/116 mmHg. Creatinine has risen from 70 to 168 micromol/L and urinalysis shows mild proteinuria. She recently received prednisolone 50 mg daily. What is the most appropriate management?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — ACE inhibitor therapy and urgent renal specialist care

Scleroderma renal crisis causes abrupt hypertension and renal failure, often after corticosteroids. ACE inhibitor therapy is central and should start urgently.

Reference: Therapeutic Guidelines: Rheumatology; Australian rheumatology practice principles