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SIADH — RACP Written MCQ

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HardEndocrinologySIADHRACP Written

A 61-year-old man with small cell lung cancer has confusion and seizures. Sodium is 112 mmol/L, serum osmolality is low, urine osmolality is 620 mOsm/kg and urine sodium is 74 mmol/L. He is clinically euvolaemic. What is the most likely cause?

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Correct answer: DSyndrome of inappropriate antidiuretic hormone secretion

Euvolaemic hypotonic hyponatraemia with inappropriately concentrated urine and high urine sodium in small cell lung cancer is SIADH.

Reference: Therapeutic Guidelines: Endocrinology; AMH