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Hyperosmolar hyperglycaemic state — RACP Written MCQ

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HardEndocrinologyHyperosmolar hyperglycaemic stateRACP Written

A 74-year-old woman with type 2 diabetes is drowsy after 3 days of polyuria and poor intake. Glucose is 46 mmol/L, osmolality 338 mOsm/kg, pH 7.34 and ketones are 0.8 mmol/L. Sodium is 154 mmol/L. What is the most likely diagnosis?

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Correct answer: CHyperosmolar hyperglycaemic state

Severe hyperglycaemia, marked hyperosmolality, dehydration and minimal ketosis indicate hyperosmolar hyperglycaemic state.

Reference: Therapeutic Guidelines: Endocrinology; AMH