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Myasthenia gravis — RACP Written MCQ

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EasyNeurologyMyasthenia gravisRACP Written

A 34-year-old woman has fluctuating ptosis, diplopia and dysphagia. Symptoms worsen during the day. Examination shows fatigable upward gaze and normal reflexes. Acetylcholine receptor antibody is positive. What is the most likely diagnosis?

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Correct answer: EMyasthenia gravis

Fatigable ocular and bulbar weakness with acetylcholine receptor antibodies is typical of myasthenia gravis.

Reference: Australian stroke and neurology guideline principles; Therapeutic Guidelines