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Guillain-Barre syndrome — RACP Written MCQ

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HardNeurologyGuillain-Barre syndromeRACP Written

A 41-year-old man develops ascending weakness 10 days after gastroenteritis. Reflexes are absent, facial weakness is present and forced vital capacity has fallen from 3.2 L to 1.8 L over 6 hours. CSF protein is elevated with few cells. What is the most important next step?

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Correct answer: D — Intravenous immunoglobulin and respiratory monitoring in hospital

Guillain-Barre syndrome with falling vital capacity needs urgent inpatient respiratory monitoring and disease-modifying treatment with IVIG or plasma exchange.

Reference: Australian stroke and neurology guideline principles; Therapeutic Guidelines