skip to main content

Coeliac disease — RACP Written MCQ

Instant feedback + full explanation. One question, done properly.

HardGastroenterology/HepatologyCoeliac diseaseRACP Written

A 32-year-old woman has bloating, iron deficiency and intermittent diarrhoea. Tissue transglutaminase IgA is strongly positive and total IgA is normal. She has already reduced gluten intake. What is the most appropriate investigation?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Upper endoscopy with duodenal biopsy while consuming gluten

Coeliac disease is confirmed with duodenal biopsy, ideally while the patient is consuming gluten to avoid false-negative histology.

Reference: Therapeutic Guidelines: Gastrointestinal; Gastroenterological Society of Australia guidance