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Allergic bronchopulmonary aspergillosis — RACP Written MCQ

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HardRespiratoryAllergic bronchopulmonary aspergillosisRACP Written

A 36-year-old man with asthma has recurrent fleeting pulmonary opacities and brown sputum plugs. Eosinophils are 1.4 x 10^9/L, total IgE is markedly elevated and CT shows central bronchiectasis. What is the most likely diagnosis?

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Correct answer: E — Allergic bronchopulmonary aspergillosis

Asthma, eosinophilia, very high IgE, mucus plugging and central bronchiectasis are classic for allergic bronchopulmonary aspergillosis.

Reference: Australian Asthma Handbook; TSANZ guidance; Therapeutic Guidelines: Respiratory