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Postmenopausal bleeding — RACGP Fellowship MCQ

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HardWomen's health and O&GPostmenopausal bleedingRACGP Fellowship

A 66‑year‑old woman reports new postmenopausal bleeding. She stopped menopausal hormone therapy five years ago. Speculum examination shows no cervical lesion and cervical screening is up to date. Haemoglobin is 121 g/L. What is the most appropriate investigation?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: CTransvaginal ultrasound to assess endometrial thickness with gynaecology referral based on findings

Explanation lettering: E = shown as A · A = shown as E

All postmenopausal bleeding must be investigated to exclude endometrial malignancy. Following normal speculum exam and up‑to‑date cervical screening, Australian guidelines advise transvaginal ultrasound (TVUS) as the investigation of choice to measure endometrial thickness; a thickness >4 mm necessitates endometrial sampling via referral to gynaecology. Reassurance alone (A) is unsafe. Antibiotics (B) are inappropriate without infection. Hormone therapy (D) is contraindicated before excluding pathology. Measuring FSH (E) is unnecessary, as clinical menopause is already established.

Reference: Independent learning program for GPs (RACGP, 2025/26) and Managing patients with symptoms of cervical cancer (Australian Department of Health, 10 March 2026), https://gplearning.racgp.org.au/Content/check/2013/PDF/June.pdf