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Convulsive status epilepticus — SCE Neurology MCQ

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HardEpilepsyConvulsive status epilepticusSCE Neurology

A patient has irregular stimulus-sensitive distal upper-limb jerks. Surface EMG bursts are brief, but routine EEG shows no obvious spike before individual jerks. Which paired neurophysiological finding would most strongly support cortical myoclonus?

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Correct answer: AA pre-jerk cortical potential on back-averaging with giant somatosensory evoked potentials

Explanation lettering: D = shown as C · C = shown as D

A is correct: cortical myoclonus may have no visible event on routine EEG, but jerk-locked back-averaging can reveal a time-locked cortical discharge preceding the EMG jerk, while giant SSEPs demonstrate cortical hyperexcitability. B supports continuous motor activity such as stiff-person spectrum disease. C is orthostatic tremor. D is peripheral nerve hyperexcitability. E, especially with variable long-duration axial jerks, points towards functional propriospinal myoclonus rather than a cortical generator.

Reference: Myoclonus: a pragmatic approach: https://pn.bmj.com/content/12/4/215