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Uraemic pruritus in conservative care — ESENeph MCQ

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ModerateActive Supportive Kidney CareUraemic pruritus in conservative careESENeph

A 69-year-old man with ESKD chooses active supportive care rather than dialysis. He has distressing uraemic pruritus, insomnia and restless legs; phosphate is 2.1 mmol/L and calcium is 2.32 mmol/L. Skin is dry without rash and there is no cholestasis. What is the most appropriate management?

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Correct answer: EOptimise emollients, phosphate control and symptom-directed therapy

Uraemic pruritus in conservative kidney care should be managed actively with skin care, phosphate control, medication review and symptom-directed treatments. Dialysis may improve symptoms for some patients, but it should not be started against an informed care preference. NSAIDs can worsen kidney function and cause harm. The pearl is that conservative kidney management includes proactive symptom control rather than non-treatment.

Reference: NICE NG107; Renal Medicine 2022 Curriculum