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Osteoporosis drug holiday misconception — NDEB AFK MCQ

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ModerateOral SurgeryOsteoporosis drug holiday misconceptionNDEB AFK

A 72-year-old taking weekly oral alendronate for osteoporosis needs a simple extraction. She has no cancer history and no exposed bone. What is the most important consideration?

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Correct answer: C — Assess MRONJ risk without assuming extraction is contraindicated

Oral bisphosphonate therapy for osteoporosis is a risk factor for MRONJ, but it does not automatically contraindicate necessary extraction. The risk assessment should consider duration, comorbidities, infection, surgical trauma, and alternatives. The pearl is to discuss risk, use atraumatic technique, and avoid leaving active dental infection untreated.

Reference: Canadian oral medicine/oral surgery references; NDEB KSAs 2024