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Ovulation assessment in irregular cycles — DRCOG MCQ

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HardSubfertilityOvulation assessment in irregular cyclesDRCOG

A woman with 42-day cycles had a low serum progesterone on cycle day 21 during infertility assessment. What should be done to assess ovulation more accurately?

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Correct answer: B — Repeat progesterone about seven days before the expected period

The best answer is “Repeat progesterone about seven days before the expected period”. Mid-luteal progesterone should be timed to the individual cycle, about seven days before the expected next period rather than fixed to day 21. In long or irregular cycles, later testing and sometimes weekly sampling may be needed before concluding that ovulation is absent.

Reference: NICE NG257: Fertility problems: https://www.nice.org.uk/guidance/ng257/chapter/recommendations