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Autosomal dominant polycystic kidney disease aneurysm screening — ABIM Board MCQ

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ModerateNephrologyAutosomal dominant polycystic kidney disease aneurysm screeningABIM Board

A 38-year-old man with autosomal dominant polycystic kidney disease asks about screening for intracranial aneurysm. His mother died from subarachnoid hemorrhage at age 45. He has no neurologic symptoms. Which of the following would you recommend?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: CScreening brain MRA because of family history of aneurysmal hemorrhage

ADPKD patients with a family history of intracranial aneurysm or subarachnoid hemorrhage are candidates for screening with noninvasive MRA. Universal screening of all asymptomatic patients is individualized.

Reference: KDIGO 2024 CKD Guideline; ADPKD Consensus Guidance