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Pheochromocytoma — ABIM Board MCQ

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ModerateEndocrinology/MetabolismPheochromocytomaABIM Board

A 44-year-old man has episodic headaches, palpitations, diaphoresis, and hypertension. Plasma free metanephrines are markedly elevated and CT shows a 4-cm adrenal mass. Which of the following is the most appropriate management?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Begin alpha-adrenergic blockade before beta-blockade and adrenalectomy

Pheochromocytoma management requires preoperative alpha blockade, volume expansion, then beta blockade if needed after adequate alpha blockade. Biopsy is avoided until pheochromocytoma is excluded.

Reference: Endocrine Society Pheochromocytoma and Paraganglioma Guideline