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Postmenopausal osteoporosis — ABIM Board MCQ

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ModerateGeneral Internal MedicinePostmenopausal osteoporosisABIM Board

A 67-year-old woman has a fragility distal radius fracture. DXA shows femoral neck T-score minus 2.6. Calcium intake is low, 25-hydroxyvitamin D is 18 ng/mL, creatinine clearance is 74 mL/min, and dental health is stable. Which of the following is the most appropriate management?

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Correct answer: BVitamin D repletion, calcium optimization, weight-bearing exercise, and bisphosphonate therapy

Osteoporosis by DXA or fragility fracture warrants fracture-risk reduction with lifestyle optimization, vitamin D repletion, calcium adequacy, fall prevention, and pharmacologic therapy such as an oral bisphosphonate when no contraindication exists.

Reference: Endocrine Society Osteoporosis Guideline; National Osteoporosis Foundation Clinician Guide