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Post-myocardial infarction secondary prevention — ABIM Board MCQ

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HardCardiovascularPost-myocardial infarction secondary preventionABIM Board

A 63-year-old had an uncomplicated MI treated with PCI 15 months ago. LVEF is 55%; he has no angina, arrhythmia or hypertension but reports fatigue and resting pulse 46/min on metoprolol. Which recommendation is best?

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Correct answer: AReduce beta-blocker therapy while maintaining other secondary prevention

Beyond one year after MI, beta-blocker continuation should be reassessed when LVEF is preserved and there is no other indication, particularly with symptomatic bradycardia. Ivabradine is not indicated, and statin and antiplatelet secondary prevention should not be withdrawn for this reason.

Reference: 2025 ACC/AHA Guideline for Acute Coronary Syndromes: https://www.ahajournals.org/doi/10.1161/CIR.0000000000001309