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Cyanide toxicity from smoke inhalation — ABEM Board MCQ

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HardToxicologyCyanide toxicity from smoke inhalationABEM Board

A 38-year-old warehouse worker presents as triage level 1 after smoke inhalation from burning plastics. He is confused and hypotensive with severe lactic acidosis; carboxyhemoglobin is mildly elevated. Which of the following is the most important immediate intervention?

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Correct answer: AHydroxocobalamin

Smoke inhalation with cardiovascular collapse and marked lactic acidosis suggests cyanide toxicity; hydroxocobalamin is an appropriate antidote.

Reference: CDC/ATSDR cyanide guidance; ABEM EM Model