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Multiple sclerosis pseudo-relapse — RCPSC IM MCQ

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ModerateNeurologyMultiple sclerosis pseudo-relapseRCPSC IM

A 58-year-old man with relapsing-remitting multiple sclerosis develops worsening leg weakness and urinary urgency during a febrile urinary tract infection. MRI brain and spine show no new enhancing lesions. Symptoms return to baseline after antibiotics and defervescence. What is the most likely cause?

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Correct answer: C — Pseudo-relapse triggered by infection

Transient worsening of previous MS symptoms during infection without new MRI activity is a pseudo-relapse, not a new inflammatory relapse.

Reference: Canadian neurological practice guidance